What Are Some Good Metallica/slayer/megadeth Type Lead Guitar Settings?

What a great lead guitar question:

Question: Hello I have a vlh 15 amp with an eminence speaker and it has a megadrive/clean mix and a straight clean bypass channel (megadrive has gain,tone,and volume and clean has low,mid,high,reverb and reverb. My effects are Jekyll and Hyde (overdrive/distortion pedal. An ibanez ts808 tube screamer. A BOSS CH-1 super chorus. A crybaby standard wah and a Jackson v I forget what series I was curious about suggested settings for all these not factory settings unless you think they sound best I was trying to play rhythm and lead together but if that’s not possible I don’t want to but a multi-effects board so please don’t suggest any I don’t like them and also thanks for all the answers.
Answer: In case you didn’t realize it, you asked this in Beer, Wine & Spirits. If you want answers, you should ask this in Rock & Pop.

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